800.788.8108

Book Online or Call Us!

Cruise Results

Cruises Found: 621

Sort:   Price   |   Departure Date   |   Length

8-night Lower Mississippi River Cruise

OFFER ID 1592144

Select

Supplier:
American Cruise Lines
Ship:
American Melody
Destination:
New Orleans/Memphis
Dates:
11/12/2027
Length:
8 Days
CALL

7-night Highlights of the Mississippi Cruise

OFFER ID 1592160

Select

Supplier:
American Cruise Lines
Ship:
American Melody
Destination:
Roundtrip New Orleans
Dates:
03/02/2027
Length:
7 Days
CALL

7-night Highlights of the Mississippi Cruise

OFFER ID 1592161

Select

Supplier:
American Cruise Lines
Ship:
American Melody
Destination:
Roundtrip New Orleans
Dates:
03/08/2027
Length:
7 Days
CALL

7-night Highlights of the Mississippi Cruise

OFFER ID 1592162

Select

Supplier:
American Cruise Lines
Ship:
American Melody
Destination:
Roundtrip New Orleans
Dates:
03/14/2027
Length:
7 Days
CALL

7-night Highlights of the Mississippi Cruise

OFFER ID 1592163

Select

Supplier:
American Cruise Lines
Ship:
American Melody
Destination:
Roundtrip New Orleans
Dates:
03/20/2027
Length:
7 Days
CALL

7-night Highlights of the Mississippi Cruise

OFFER ID 1593595

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
Roundtrip New Orleans
Dates:
10/09/2026
Length:
7 Days
CALL

8-night Lower Mississippi River Cruise

OFFER ID 1593597

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
10/15/2026
Length:
8 Days
CALL

11-night Mississippi Explorer Cruise

OFFER ID 1593599

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
10/29/2026
Length:
11 Days
CALL

8-night Lower Mississippi River Cruise

OFFER ID 1593614

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
02/19/2027
Length:
8 Days
CALL

8-night Lower Mississippi River Cruise

OFFER ID 1593615

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
03/05/2027
Length:
8 Days
CALL

8-night Lower Mississippi River Cruise

OFFER ID 1593616

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
03/19/2027
Length:
8 Days
CALL

8-night Lower Mississippi River Cruise

OFFER ID 1593617

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
04/02/2027
Length:
8 Days
CALL

8-night Lower Mississippi River Cruise

OFFER ID 1593618

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
04/16/2027
Length:
8 Days
CALL

8-night Lower Mississippi River Cruise

OFFER ID 1593619

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
04/30/2027
Length:
8 Days
CALL

8-night Lower Mississippi River Cruise

OFFER ID 1593620

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
05/14/2027
Length:
8 Days
CALL

8-night Lower Mississippi River Cruise

OFFER ID 1593622

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
11/09/2027
Length:
8 Days
CALL

8-night Lower Mississippi River Cruise

OFFER ID 1593623

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
11/23/2027
Length:
8 Days
CALL

8-night Lower Mississippi River Cruise

OFFER ID 1593624

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
12/07/2027
Length:
8 Days
CALL

22-night Complete Mississippi River Cruise

OFFER ID 1593626

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/St. Paul
Dates:
06/11/2027
Length:
22 Days
CALL

11-night Mississippi Explorer Cruise

OFFER ID 1593651

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
New Orleans/Memphis
Dates:
10/08/2027
Length:
11 Days
CALL

7-night Highlights of the Mississippi Cruise

OFFER ID 1593664

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
Roundtrip New Orleans
Dates:
10/28/2027
Length:
7 Days
CALL

7-night Highlights of the Mississippi Cruise

OFFER ID 1593665

Select

Supplier:
American Cruise Lines
Ship:
American Serenade
Destination:
Roundtrip New Orleans
Dates:
11/03/2027
Length:
7 Days
CALL

14-night The Big Easy To The Gateway City Cruise

OFFER ID 1594498

Select

Supplier:
Viking
Ship:
Viking Mississippi
Destination:
New Orleans/St. Louis (Alton)
Dates:
07/18/2026
Length:
14 Days
CALL

21-night Mississippi River Odyssey Cruise

OFFER ID 1594499

Select

Supplier:
Viking
Ship:
Viking Mississippi
Destination:
New Orleans/St. Paul
Dates:
07/18/2026
Length:
21 Days
CALL

10-night New Orleans To Memphis Cruise

OFFER ID 1594510

Select

Supplier:
Viking
Ship:
Viking Mississippi
Destination:
New Orleans/Memphis
Dates:
10/17/2026
Length:
10 Days
CALL

Prev Next

Modify Cruise Search

To select multiple options, hold the CTRL-key. (CMD on Mac)

Between
And

Reset

CRUISE SEARCH CRUISE ADVANCED SEARCH CRUISE LINES DESTINATIONS SIGNATURE COLLECTION CRUISE PORTS

Safe & Secure Booking

Best Value Guarantee

Buy with Confidence

Cruise OnSale
a division of National Discount Cruise
5000 W Tilghman Street, Suite 305
Allentown, PA 18104

(800) 788-8108 Toll Free

Monday - Thursday: 9:30am - 9:00pm (EST)
Friday: 9:30am - 6:00pm (EST)
Saturday: 10:00am - 4:00pm (EST)
Sunday: Closed

© Copyright 2026. All Rights Reserved. CruiseOnSale.

Travel content powered by advaia.com